extra Flashcards

1
Q

what endocrine tissue does GH work on and what does this release

A

liver
IGF1

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2
Q

3 LAYERS OF ADRENAL CORTEX

A

zona glomerulosa
zona fasiculata
zona reticularis

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3
Q

secretes steroids

A

adrenal cortex

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4
Q

secretes catecholamines

A

adrenal medulla

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5
Q

formed from neural ectoderm

A

adrenal medulla

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6
Q

formed from medoderm

A

adrenal cortex

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7
Q

what secretes cortisol and androgesn

A

ZFR- zones fasiculata and reticularis

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8
Q

how does blood flow in adrenal cortex

A

out to in

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9
Q

angtiotensin, K and ACTH purpose

A

SCC enzyme inducing

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10
Q

what does SCC produces

A

DHEA which produces steroid hormones

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11
Q

upregulates LDL receptors

A

ACTH in all 3 zones

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12
Q

what do tropic hormones do

A

stimulate and maintain cellualar growth of their target endocrine tissues
atrophy or hypertrophy

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13
Q

catabolic steroid

A

cortisol

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14
Q

androgens- anabolic or catabolic

A

anabolic

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15
Q

what causes secretion of cortisol

A

stress and dinural rhythm

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16
Q

permissive for catecholamines

17
Q

when does hemmorage occur

A

in absence of cortisol which is permissive for catecholamines which cuase constriction of blood vessels

18
Q

what does cortisol protective during

A

ACUTE stress

19
Q

primary insufficiency of addisons disease

A

adrenal cortex destroyed by autoimmune action

20
Q

other hormones secreted during stress

A

cortisol, ADH, glucagon, epinephrine, aldosterone, GH

21
Q

what displays synergysm

A

glycagon, cotisol, epinephrine
inc blood glucose

22
Q

where are c cells

A

in thyroid

23
Q

what enzyme is needed for thyroid hormone production

A

thyroid peroxidase

24
Q

MIT

A

tyrosine and I

25
supply of thyroid hormones
2-3 months
26
bioactive forms of thyroid hormones
free T3 and T4 in eqm with bound TBG
27
where does deiodination of T4 take place
liver and kidney
28
biological activity features of thyroid hormones
BMR (inc with hyperthyroidism) growth and development CNS developemnt and function low mental age with hypothyroidism essential for mentation enhances SNS activity- inc catecholamine receotrs inc speed of nervous reflexes
29
has sympathomimetic activity
thyroid hormones
30
hypothyroidism
low secreiton of thyroid hormones
31
hypothyroidism due to
autoimmune- thyroditis and subsequent fibrosis and low TSH and TRH
32
hypothyroidism due to
autoimmune- thyroditis and subsequent fibrosis and low TSH and TRH low iodine
33
hyperthyroidism due to
autoimmune- graves disease or thyrotoxicosis- TSI stimulates TSH receptors thyroid tumor excess TSH or TRH
34
when does myxedemia happen
hypothyroidism
35
what is myxedemia
puffy doughy appearance
36
causes elevated blood cholesterol
hypothyroidism
37
what causes exophthalamos
hyperthyroidism