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MED 310 > extra > Flashcards

extra Flashcards

1
Q

what endocrine tissue does GH work on and what does this release

A

liver
IGF1

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2
Q

3 LAYERS OF ADRENAL CORTEX

A

zona glomerulosa
zona fasiculata
zona reticularis

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3
Q

secretes steroids

A

adrenal cortex

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4
Q

secretes catecholamines

A

adrenal medulla

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5
Q

formed from neural ectoderm

A

adrenal medulla

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6
Q

formed from medoderm

A

adrenal cortex

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7
Q

what secretes cortisol and androgesn

A

ZFR- zones fasiculata and reticularis

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8
Q

how does blood flow in adrenal cortex

A

out to in

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9
Q

angtiotensin, K and ACTH purpose

A

SCC enzyme inducing

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10
Q

what does SCC produces

A

DHEA which produces steroid hormones

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11
Q

upregulates LDL receptors

A

ACTH in all 3 zones

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12
Q

what do tropic hormones do

A

stimulate and maintain cellualar growth of their target endocrine tissues
atrophy or hypertrophy

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13
Q

catabolic steroid

A

cortisol

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14
Q

androgens- anabolic or catabolic

A

anabolic

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15
Q

what causes secretion of cortisol

A

stress and dinural rhythm

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16
Q

permissive for catecholamines

17
Q

when does hemmorage occur

A

in absence of cortisol which is permissive for catecholamines which cuase constriction of blood vessels

18
Q

what does cortisol protective during

A

ACUTE stress

19
Q

primary insufficiency of addisons disease

A

adrenal cortex destroyed by autoimmune action

20
Q

other hormones secreted during stress

A

cortisol, ADH, glucagon, epinephrine, aldosterone, GH

21
Q

what displays synergysm

A

glycagon, cotisol, epinephrine
inc blood glucose

22
Q

where are c cells

A

in thyroid

23
Q

what enzyme is needed for thyroid hormone production

A

thyroid peroxidase

24
Q

MIT

A

tyrosine and I

25
Q

supply of thyroid hormones

A

2-3 months

26
Q

bioactive forms of thyroid hormones

A

free T3 and T4 in eqm with bound TBG

27
Q

where does deiodination of T4 take place

A

liver and kidney

28
Q

biological activity features of thyroid hormones

A

BMR (inc with hyperthyroidism)
growth and development
CNS developemnt and function

low mental age with hypothyroidism
essential for mentation
enhances SNS activity- inc catecholamine receotrs
inc speed of nervous reflexes

29
Q

has sympathomimetic activity

A

thyroid hormones

30
Q

hypothyroidism

A

low secreiton of thyroid hormones

31
Q

hypothyroidism due to

A

autoimmune- thyroditis and subsequent fibrosis and low TSH and TRH

32
Q

hypothyroidism due to

A

autoimmune- thyroditis and subsequent fibrosis and low TSH and TRH
low iodine

33
Q

hyperthyroidism due to

A

autoimmune- graves disease or thyrotoxicosis- TSI stimulates TSH receptors
thyroid tumor
excess TSH or TRH

34
Q

when does myxedemia happen

A

hypothyroidism

35
Q

what is myxedemia

A

puffy doughy appearance

36
Q

causes elevated blood cholesterol

A

hypothyroidism

37
Q

what causes exophthalamos

A

hyperthyroidism

MED 310 (47 decks)

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