Disfunção Plaquetaria Flashcards

1
Q

Processos da plaquetas:

A

Lesão endotelial –> Adesão –> Ativação –> Agregação

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2
Q

Adesão , qual proteína adere?

A

Glicoproteína 1b + fator de Von Willebrand (FvWb)

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3
Q

Ativação , sinais que atraem plaquetas:

A

Adp…. (Via receptor p2y12)..

Tromboxane A2

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4
Q

Onde age o Clopidogrel e o AAS?

A

Clopidogrel - inibe o ADP..

AAS - inibe a ciclooxenase que produz o tromboxane

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5
Q

Agregação, proteína

A

IIb IIIa

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6
Q

Problema hereditário : Bernard-Soulier

A

Ib

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7
Q

Problema hereditário: Glanzmann

A

IIbIIIa

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8
Q

Um macete para gravar

A

Primeiro vem a Ib e segundo a IIbIIIa

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9
Q

Principal deficiência hereditária ?

A

Deficiência do fator de Von Willebrand

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