Class IV Antiarrhythmics Flashcards
Names Class IV Antiarrhythmics
Non dihydropyridine calcium channel blockers
Verapamil
(“very Vanilla”)
Diltiazem
(“Delicious dark choclate”)
Class IV Antiarrhythmics MOA
Non-Dihydropyridine Calcium Channel Blockers
-Block L-type voltage gated Calcium channels in the heart thus block calcium current in the SA and AV nodes
(“L shaped nozzles on wall”)
(“Notes on music sheet”)
- Exert a greater effect on tissues that fire more frequently that use a calcium current
-non-dihydropyridine CCB’s prolong phase 4 of the nodal action potential decreased pacemaker activity, prolonged conduction time and refractory period
(“pianist sliding up the keys”)
-non-dihydropyridine CCB’s decrease atrioventricular conduction
(“Disconnected bottom of heart shaped lamp”)
Class IV Antiarrhythmics can treat …
-treat supraventricular arrhythmias (A.FIB with RVR)
(“Illuminated top of the heart shaped lamp”)
-useful in atrial fibrillation and flutter
(“tv showing Irregularly irregular signal”)
-prevents rapid ventricular response in A Fib and Flutter
(“heart shaped metronome on piano”)