Class II Antiarrhythmics Flashcards

1
Q

Class II Antiarrhythmics are …

A

Beta Blockers
(“muted Beta Bugle”)

Non Selective

  • *Proprano**lol
  • *Sota**lol
  • *Timo**lol
  • *Nado**lol

Selective

“A-BEAM”

  • *Acebuto**lol
  • *Bisopro**lol
  • *Esmo**lol
  • *Ateno**lol
  • *Metopro**lol
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2
Q

Beta Blockers MOA
(“muted Beta Bugle”)

A

-blocking sympathetic input to SA and AV nodes
(“SA , AV Notes”)

-decrease cAMP , leads to closure of membrane calcium channels, preventing the upstroke of AV nodal action potential
(“Torn Band Camp poster”)
(“Crushed calci-yum ice cream cartons on the floor”)

-prolong phase 4 of the nodal action potential decreased pacemaker activity, prolonged conduction time and refractory period
(“Ella Fitzgerald sliding up the piano keys”)

-decrease atrioventricular conduction
(“disconnected bottom of heart shaped lamp”)

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3
Q

Class II Antiarrhythmics can be used to treat …

A

-supraventricular arrhythmias (Afib and RVR)
(“upper part of heart shaped lamp is lit”)

-useful in atrial fibrillation (and flutter)
(“Irregularly irregular static signal”)

-prevent rapid ventricular response in atrial fibrillation and flutter-“rate control”
[does not fix the atrial fibrillation]
(“heart shaped metronome”)

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4
Q

Acute supraventricular arrhythmias can be treated with …

A

IV Beta blokcer e.g. - Esmolol

(“poison ivy”)

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5
Q

Class II Antiarrhythmics Side effects

A

-Beta blockers can cause heart block

  • heart block manifests as a prolonged PR interval on EKG
    (“suited reporter interviewed by Public relations”)

(“louie’s hat shielding heart”)

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