Class II Antiarrhythmics Flashcards
Class II Antiarrhythmics are …
Beta Blockers
(“muted Beta Bugle”)
Non Selective
- *Proprano**lol
- *Sota**lol
- *Timo**lol
- *Nado**lol
Selective
“A-BEAM”
- *Acebuto**lol
- *Bisopro**lol
- *Esmo**lol
- *Ateno**lol
- *Metopro**lol
Beta Blockers MOA
(“muted Beta Bugle”)
-blocking sympathetic input to SA and AV nodes
(“SA , AV Notes”)
-decrease cAMP , leads to closure of membrane calcium channels, preventing the upstroke of AV nodal action potential
(“Torn Band Camp poster”)
(“Crushed calci-yum ice cream cartons on the floor”)
-prolong phase 4 of the nodal action potential decreased pacemaker activity, prolonged conduction time and refractory period
(“Ella Fitzgerald sliding up the piano keys”)
-decrease atrioventricular conduction
(“disconnected bottom of heart shaped lamp”)
Class II Antiarrhythmics can be used to treat …
-supraventricular arrhythmias (Afib and RVR)
(“upper part of heart shaped lamp is lit”)
-useful in atrial fibrillation (and flutter)
(“Irregularly irregular static signal”)
-prevent rapid ventricular response in atrial fibrillation and flutter-“rate control”
[does not fix the atrial fibrillation]
(“heart shaped metronome”)
Acute supraventricular arrhythmias can be treated with …
IV Beta blokcer e.g. - Esmolol
(“poison ivy”)
Class II Antiarrhythmics Side effects
-Beta blockers can cause heart block
- heart block manifests as a prolonged PR interval on EKG
(“suited reporter interviewed by Public relations”)
(“louie’s hat shielding heart”)