Alpha agonists/ant-agonists Flashcards

1
Q

Name the α2 Agonists

A

Clonidine
(“Raul holding the claw”)

α-methyldopa
(“α shaped rope”)

Tizanidine
(“to-x-tine”)

*Brimonidine*
(“brim of eyeball shaped hat”)

*not on alpha drugs sketchy

-α2 agonists affect the CNS
(“Brain shaped platform”)

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2
Q

Clonidine

(“white shirt Raul holding Le-CLAW”)

A

-α2 agonist (“raul holding 2 lit candles”)

-has CNS effects
(“brain shaped platform on floor”)

-_inhibits t_he sympathetic tone and reduces blood pressure therefore is useful in treatment of hypertension
(crossd out “sympathy” under the stage next to “high pressure pipes”)

-useful in managment of Tourette’s syndrome
(“tourette’s marionette”)

-useful in treatment of ADHD
(Raul aint even lookin at the play he looking at “Distracting mirror”)

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3
Q

α-MethylDopa

(“α-methylROPA”)

A

-α2 agonist
(“whtie lady holding 2 lit candles”)

-has CNS effects
(“brain shaped platform”)

-useful for treatment of Gestational Hypertension

(“white lady is pregnant” “high pressure pipes next to α-methyl ropa”)

  • can cause Lupus-like syndrome
    (“sneaky wolf next to white lady”)
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4
Q

Tizanidine

(“to-x-tine”)

A

-α2 agonist (“2 lit candles next to chair”)

-central acting muscle relaxant
(“Relaxing chair”)

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5
Q

Name non-selective α antagonists

A

Phentolamine
(“Phantom of the Opera standing on chandelier”)

Phenoxybenzamine
(“phoenix tattoo on Phantom’s chest”)

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6
Q

Phentolamine

(“Phantom of the Opera standing on chandelier”)

A

-α1 α2 non selective antagonist
(“phantom of the Opera standing on chandelier with extinguished single and double candles”)

-reversible

-causes vasodilation via α1 antagonistic effect
(“phantom of the opera has dilated sleeves”)

  • may cause orthostatic Hypotension (“tilt table”) via α antagonis,and as a result reflex tachycardia
    (doc. hitting leg with heart reflex hammer”)
  • useful in treatment of cocaine toxicity
    (“hot cocoa”)

-useful in case of Hypertensive crisis in which wine and cheese that contain tyramine(sympathomimetic) were consumed alongside MAO inhibitors

(“wine and cheese on table protected by mouse trap”)

-useful in treatment of Pheochromocytoma
(“frozen colorful dessert”)

  • headaches (“kid having brain freeze”)
  • ​hypertention
  • ​palpitations
  • ​sweating

*use pre/interoperatively

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7
Q

Phenoxybenzamine

(“Phoenix tattoo on Phantom’s chest”)

A
  • α1 and α2 **non-selective antagonist
  • irrevesible**

(“pheonix tattoo is irreverisble , permanent”)

-useful for treatment of Pheochromoctoma but usually given few days in advance to surgery

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8
Q

name the selective α1 antagonists

A

-“osin” suffix for all (“Opera singer”)

Praz /Teraz/Doxaz/Tamsul-OSIN

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9
Q

Terazosin

(“opera singer” -osin)

*also α1 antagonists in general*

A

-α1 antagonist
(“opera singer holding extinguished single candle”)

-causes Vasodilation
(“opera singer has dilated sleeves”)

-relaxes smooth muscles in urethra and prostate and therefore is useful treatment for BPH
(“opera singer sitting on banister that compresses his prostate”)

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10
Q

Prazosin

(_“pray_ing opera singer”)

A

-α1 antagonist
(“single extinguished candle next to praying opera singer”)

-can cause orthostatic hypotension
(“tilt table on stage”)

  • can be used to treat PTSD
    (praying opera singer holding dog tags saying “PT” “SD”)
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11
Q

Mirtazapine

(“Mirth and Misery”)

A

-atypical antidepressant

-α2 antagonist {+other receptors}
(“2 extinguished candles below 2 masks”)

-enhances serotonin release and useful for treatment of depression
(“happy mask / sad mask”)

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