Câncer de Pele Flashcards

1
Q

Camadas da epiderme

A
Queratinocitos
Cornea
Granulosa
Espinhosa
Basal
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2
Q

Fatores de risco Ca de pele

A

Nevo melanocítico:
> 50, displasico, congenito

Hist familiar ou pessoal

Genetico: CDK2NA
Fenotipo claro (fitzpatrick 1/2)
UV-B

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3
Q

Clinica Ca de pele

A
Assimetria
Borda irregular
Cor variada (>2)
Diâmetro (>6mm)
Evoluçao (tamanho, formato, sintomas)
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4
Q

Tipos de melanoma

A

Extensivo superficial (+comum)
Nodular
Acral
Lentigo maligno

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5
Q

Melanoma extensivo superficial

A

Lento
Radial
Macula
Dorso/perna

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6
Q

Melanoma nodular

A

+ grave
Rapido
Vertical
Dorso/ cabeça/ pescoço

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7
Q

Melanoma acral

A

Lento
Palmo plantar
Negros

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8
Q

Melanoma lentigo maligno

A

+ lento
Cabeça e maos
+ idosos

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9
Q

Diagnostico ca de pele

A

Dermatoscopia
Biópsia excisional (margem 2mm)
Insicional se: extensa/ face

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10
Q

Tratamento melanoma

A

Ampliar margem bx

Breslow

In situ: 0,5- 1 cm
< 1mm: 1cm
1-2mm: 1-2cm
>2mm: >=2cm

Acometimento ganglionar: linfadenectomia

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11
Q

Pesquisa linfonodo sentinela

A

Breslow > 0,76 mm

<0,76 se: ulceraçao, regressao, mitose

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12
Q

Tto adjuvante melanoma

A

IFN-alfa ou QT: >4mm ou LS+

VEMURAFENIB: metástases

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13
Q

Tto e diag carcinoma baso e espinocelular

A

Dx: bx
Tto: curetagem/ eletrocoagulacao/ exérese

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14
Q

Epidemio CBC e espino

A

Fenotipo claro
Idade avançada
Homens
Radiaçao

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15
Q

Ca de pele mais comum

A

CBC

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16
Q

Caracteristicas CBC

A
2/3 suleriores da face
Relaçao com alta exposiçao solar
Nódulo ulcerativo
Perolado+ telangiectasias
Pouco agressivo
Invasao local
Recidivas
17
Q

Epidemio CEC

A

1/3 inferior face (labios)
> risco metastases
Negros

18
Q

Clinica CEC

A

Relaçao com exposiçao solar continua
Lesoes previas: cicatriz, HPV
+ associado aos transplantados

Invasivo: placa eritematosa ceratotica que sangra