[C] 1.58 General characteristics of the granuloma formation Flashcards
1
Q
What are granulomatous lesions?
A
Chronic inflammation in which:
- The predominant inflammatory cell is the macrophage
- These may aggregate to form a mass - granuloma
- Macrophages may also fuse to form multinucleate giant cells
2
Q
Granuloma formation: Overview
A
- Long lasting effect (chronic processes)
- Proliferation is increasingly significant
- Local lesion
- Concentric structure (different cell populations form the layers)
3
Q
Granuloma formation: Causes
A
- Pathogens (Infectious granulomas)
- Non-infectious granulomas
- Chemical agents
- Foreign bodies
- Biological materials (keratin)
4
Q
Chemical agents forming granulomas
A
- Uric acid
- Cholesterol calc
- Aluminium-hydroxide
5
Q
Give the pathogens that can cause infectious granulomas
A
- Mycobacterium spp.
- Actinomyces bovis
- Actinobacillus lignieresii
- Burkholderia mallei
- Fungi
- Parasites
6
Q
Mycobacteriosis can cause granuloma in…
A
Bo & Av
7
Q
Dermatomycosis is seen in…
A
Cat
8
Q
Examples of granuloma-forming foreign material
A
- Oils
- Plant parts
- Paraffin
- Vaseline
- Talcum
9
Q
Examples of granuloma-forming biological materials
A
- Mucus
- Hair
10
Q
Importance of cotton in granuloma formation
A
Cotton is used to make laparotomy sponges for surgery
-
Retained surgical sponge (RSS) - a surgical complication
- Also known as “gossypiboma”
- Inflammatory and neoplastic complications
11
Q
Idiopathic cause of granuloma formation
A
Feline eosinophil granuloma complex
12
Q
Morphological types of granulomas are dependent on…
A
- Cell populations building up the granuloma
- Composition and radiation of cells
- Order of the concentric layers
13
Q
Granuloma types
A
- Epitheloid type
- Pyogranuloma
- Foreign body type
14
Q
Epitheloid-type granuloma
A
15
Q
Epitheloid granuloma may be caused by…
A
-
Mycobacterium
- tuberculosis
- bovis
- Burkolderia mallei
- Fungi
- Parasite larvae
16
Q
Connective tissue type granuloma
A
18
Q
Foreign body type granuloma
A
