[A] 1.54 Suppurative inflammation

Question 1

“Suppurative” =

Answer 1

Purulent (Pus-forming)

Question 2

Suppurative/Purulent inflammation: Causes

Answer 2

Strong chemotactic stimulus

• Pyogenic bacteria
• Chemicals
• Necrotic tissue

Question 3

Suppurative/Purulent inflammation: Locations of occurance

Answer 3

• Mucosa
• Serosa → (Pyopericardium, pyothorax, pyoarthros)
• Inside organ → (Phlegmon, microabscess, abscess)

Question 4

Suppurative/Purulent inflammation: Composition

Answer 4

• Neutrophils
• Heterophils
• Lymphocytes
• Histiocytes
• RBCs
• Monocytes

Question 5

Suppurative/Purulent inflammation: Colour

Answer 5

• Grey-white, -yellow; viscous; turbid
• Fat droplets in the cytoplasm of the neutrophils
• Pathogen influences appearance
  
  • A. pyogenes - Greenish
  • P. aeruginosa - Blue-green

Question 6

Suppurative/Purulent inflammation: Consistency

Answer 6

• Watery (thin)
• Dense (thick)
• Dry

Question 7

Outcome of Suppurative/Purulent inflammation

Answer 7

• On mucous membranes
• Acute superficial - purulent catarrh
• Draining/escape
• Accumulation (empyema)

Question 8

Suppurative/Purulent inflammation: Drain/escape

Answer 8

• Through anatomical orifices
• Pyorrhoea (discharge)
• Healing

Question 9

Suppurative/Purulent inflammation: Accumulation (empyema)

Answer 9

• In the uterus - pyometra
• Chronic purulent inflammation

Question 10

Outcome of Suppurative/Purulent inflammation: On serous membranes

Answer 10

• Circulatory disturbances
  
  • Vascular injection, Haemorrhages
• Exudation, infiltration
• Accumulation (empyema)
  
  • In the thorax - Pyothorax
  • In the joint - Pyoarthros
  • In the pericardium - Pyopericardium

Question 11

Suppurative/Purulent inflammation: Types inside the organs

Answer 11

• Phlegmon
  
  • Diffusely in the tissue spaces
  • Exudation + infiltration
  • Usually in the loose connective tissue
• Microabscess
• Abscess
  
  • Circumscribed
  • Exsudation, infiltration & alteration

Question 12

Abscess: Overview

Answer 12

• No spreading
• Demarcation
• Total histolysis on the area
• Structure: “Concentric layering”
• Destruction of the wall
  
  • Discharge of the pus
  • Surfaces, cavities, blood (pyemia)

Question 13

Abscess: Zones

Answer 13

Question 14

Purulent inflammation in the skin

Answer 14

• In the epithelial layer
• Impetigo, greasy pig disease
• Staphylococcus hyicus

Question 15

Purulent inflammation in the skin: In the epithelial layer

Answer 15

• Tiny intradermal abscess (pustula)
• Between the str. corneum and granulosum

Question 16

Purulent inflammation in the skin: Impetigo, greasy pig disease

Answer 16

• Small vesicles filled with pus
• Thickened, red-brown spots (crusts)
• Widespread lesions