[B] 1.13 Infectious agents/Bacteria, viruses and fungi as causes of disease Flashcards
Infection
Spreads from animal to animal through direct or indirect route
Invasiveness
The pathogen is able to spread inside the organism
(But not all of them)
Infectious pathogens: Examples
- Parasites
- Fungi
- Bacteria
- Viruses
- Prions
Ectoparasites
Non-invasive, do not enter the organism
- Effect: Stress, weakening factor
- Vectors (may transfer other parasites/bacteria)
Endoparasites (infectious) can be either…
- Multicellular
- Unicellular
Multicellular endoparasites
Damage:
- Stress
- Weakening factor
- Tissue irritation
- Obturating effect
- Thromotisation
- Atrophy
- Autointoxication
Unicellular endoparasites
- Intracellular (cell-damage e.g babesia)
- Extracellular (E.g toxoplasma → cytotoxic products)
Fungal infections
- Mycotoxicosis
- Dermatomycosis
- Visceral mycosis
Mycotoxicosis elicits…
No infection
Dermatomycosis
- Superficial invasion: Skin, claw, hoof
- Loss of hair, irritation, stress
Visceral mycosis
- Local inflammation
- Granuloma formation
- Thalus-formation
- Thrombotisation
- Metastasis
Bacterial infections
Obligatory & Facultative pathogens
- IC bacteria
- EC bacteria
- Bacterial intoxications
- Enterosorption/Enterotoxaemia
IC bacteria
- Chlamydophila
- Rickettsia
- Damage: ~virus
EC bacteria
Exo- and endotoxins
- → Necrosis, inflammatory reaction
Bacterial intoxication
No infection
E.g Botulism
Enterosorption/Enterotoxaemia
- Pathogen proliferated in the GI tract
- Produces toxins → harmful effect
Local bacterial infection
Pathogen enters body but doesn’t spread
- Wound infection
- Navel infection
Toxin production, local tissue destructive processes
Systemic infections
Pathogen spreads in body
- Bacteraemia
- Pyaemia
- Septicaemia
- Sepsis
- Metastasis
- Bacterial thromboembolism
Viruses cause loss…
Only after infection
Obligatory intracellular pathogens
Modify the physiological metabolic processes of the infected cell
Damage caused by viruses
- Cell destruction
- Inflammatory reaction
- Proliferative effect
Prions
Cause losses after infection
- Modify cellualr metabolism
- Damage: Neuron degeneration; encephalosis
BSE