Warfarin Flashcards
What is the classification of warfarin?
Warfarin is classified as an anticoagulant.
True or False: Warfarin is a vitamin K antagonist.
True.
What is the initial recommended dosage of warfarin for adults?
The initial recommended dosage is typically 5 mg per day.
Fill in the blank: Warfarin is primarily used to prevent __________.
thromboembolism.
What is the mechanism of action of warfarin?
Warfarin inhibits vitamin K epoxide reductase, reducing the synthesis of vitamin K-dependent clotting factors.
List two indications for prescribing warfarin.
Atrial fibrillation and deep vein thrombosis.
What is a common adverse effect of warfarin?
Bleeding.
True or False: Warfarin does not have any significant drug interactions.
False.
What should be monitored regularly in patients taking warfarin?
International Normalized Ratio (INR).
What is the therapeutic INR range for most patients on warfarin?
2.0 to 3.0.
Fill in the blank: Patients on warfarin should maintain a consistent intake of __________.
vitamin K.
Name one food that can interact with warfarin.
Green leafy vegetables.
What is a major risk associated with warfarin therapy?
Hemorrhagic complications.
True or False: Warfarin can be used during pregnancy.
False.
What is the effect of alcohol on warfarin metabolism?
Alcohol can increase the effects of warfarin, leading to a higher risk of bleeding.
What is the antidote for warfarin overdose?
Vitamin K.
How does liver function affect warfarin dosing?
Impaired liver function can lead to increased warfarin effects and require dosage adjustments.
Fill in the blank: Warfarin is contraindicated in patients with active __________.
bleeding.
What is the purpose of bridging therapy when initiating warfarin?
To provide anticoagulation coverage until warfarin reaches a therapeutic level.
Name one anticoagulant that can be used as a bridge to warfarin.
Low molecular weight heparin (LMWH).
True or False: Warfarin can interact with herbal supplements.
True.
What is the role of genetic testing in warfarin therapy?
To identify genetic variations that affect warfarin metabolism and dosing.
What is a common side effect of warfarin that patients should be aware of?
Easy bruising.
Fill in the blank: Patients should report any signs of __________ while on warfarin.
unusual bleeding.
