Nitrofurantoin Flashcards

1
Q

What is the classification of Macrobid?

A

Macrobid is classified as a nitrofuran antibiotic.

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2
Q

What is the standard adult dosage of Macrobid for uncomplicated urinary tract infections?

A

The standard adult dosage is 100 mg every 12 hours for 7 days.

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3
Q

True or False: Macrobid is effective against gram-negative bacteria.

A

True.

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4
Q

What action does Macrobid perform to combat infections?

A

Macrobid works by inhibiting bacterial cell wall synthesis.

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5
Q

Fill in the blank: Macrobid is indicated for the treatment of _______.

A

uncomplicated urinary tract infections.

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6
Q

What is a common adverse effect of Macrobid?

A

A common adverse effect is gastrointestinal upset.

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7
Q

What serious adverse effect can occur with prolonged use of Macrobid?

A

Pulmonary toxicity can occur with prolonged use.

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8
Q

True or False: Macrobid can be used to treat systemic infections.

A

False.

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9
Q

What interaction should be considered when prescribing Macrobid?

A

Macrobid may interact with antacids containing magnesium.

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10
Q

What should be monitored in patients taking Macrobid?

A

Renal function should be monitored in patients taking Macrobid.

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11
Q

Fill in the blank: Macrobid is contraindicated in patients with _______.

A

significant renal impairment.

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12
Q

What is the mechanism of action of Macrobid?

A

Macrobid acts by producing reactive intermediates that damage bacterial DNA.

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13
Q

True or False: Macrobid can be used in pregnancy.

A

True, but it should be used with caution.

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14
Q

What is the recommended duration of treatment with Macrobid for UTIs?

A

The recommended duration is typically 7 days.

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15
Q

What form does Macrobid come in?

A

Macrobid is available in capsule form.

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16
Q

Fill in the blank: The trade name for nitrofurantoin is _______.

17
Q

What type of infections is Macrobid primarily used to treat?

A

Macrobid is primarily used to treat urinary tract infections.

18
Q

What is a potential side effect related to the long-term use of Macrobid?

A

Chronic pulmonary reactions may occur with long-term use.

19
Q

True or False: Macrobid can be used in children under the age of 12.

20
Q

What is a notable precaution to take when prescribing Macrobid?

A

Assess for previous hypersensitivity to nitrofuran derivatives.

21
Q

What is the effect of food on the absorption of Macrobid?

A

Macrobid should be taken with food to enhance absorption.

22
Q

Fill in the blank: Macrobid is not effective against _______.

A

systemic infections.

23
Q

What should patients be advised regarding Macrobid and urine color?

A

Patients should be advised that Macrobid may cause urine to turn a dark yellow or brown.

24
Q

What is the significance of monitoring renal function in patients taking Macrobid?

A

Renal function monitoring is important to prevent toxicity due to accumulation.

25
True or False: Macrobid can cause hemolytic anemia in patients with G6PD deficiency.
True.
26
What is the recommended pediatric dosage for Macrobid?
The pediatric dosage is typically 5-7 mg/kg/day divided every 12 hours.