Heparin Flashcards

1
Q

What is the primary classification of Heparin sodium?

A

Anticoagulant

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2
Q

True or False: Heparin sodium is used to prevent blood clots.

A

True

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3
Q

What is the typical dosage range for Heparin sodium in adults for DVT prophylaxis?

A

5,000 units every 8 to 12 hours

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4
Q

Fill in the blank: Heparin sodium works by inhibiting _____ and factor Xa.

A

thrombin

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5
Q

What is a common indication for the use of Heparin sodium?

A

Deep vein thrombosis (DVT) prevention

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6
Q

List one major adverse effect of Heparin sodium.

A

Bleeding

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7
Q

What laboratory test is commonly monitored during Heparin sodium therapy?

A

Activated Partial Thromboplastin Time (aPTT)

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8
Q

True or False: Heparin sodium can be administered orally.

A

False

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9
Q

What is the mechanism of action of Heparin sodium?

A

It enhances the activity of antithrombin III.

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10
Q

What is one contraindication for Heparin sodium use?

A

Active bleeding

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11
Q

Which of the following is a potential drug interaction with Heparin sodium? A) Aspirin B) Ibuprofen C) Both A and B

A

C) Both A and B

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12
Q

What is the recommended action if a patient experiences a significant drop in platelet count while on Heparin sodium?

A

Discontinue Heparin sodium immediately.

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13
Q

What is the effect of Heparin sodium on clotting factors?

A

It reduces thrombin and factor Xa activity.

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14
Q

Fill in the blank: Heparin sodium is primarily eliminated by the _____ system.

A

reticuloendothelial

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15
Q

True or False: Heparin sodium can be used during pregnancy.

A

True

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16
Q

What should be monitored closely in patients receiving Heparin sodium?

A

Signs of bleeding

17
Q

What is the antidote for Heparin sodium overdose?

A

Protamine sulfate

18
Q

What is the typical route of administration for Heparin sodium?

A

Subcutaneous or intravenous

19
Q

Which patient population should be carefully monitored when using Heparin sodium due to increased risk?

A

Elderly patients

20
Q

What condition may require dosage adjustment or careful monitoring of Heparin sodium?

A

Renal impairment

21
Q

Fill in the blank: Heparin sodium is often given in a _____ regimen for treatment of acute thromboembolic events.

A

bolus/infusion

22
Q

What is a possible long-term effect of Heparin sodium therapy?

A

Osteoporosis

23
Q

True or False: Heparin sodium can cause heparin-induced thrombocytopenia (HIT).

24
Q

What is the primary goal of Heparin sodium therapy?

A

To prevent thrombus formation

25
Which factor is NOT affected by Heparin sodium? A) Factor IIa B) Factor Xa C) Factor VIIa
C) Factor VIIa