Sulphamthazole/trimethoprim Flashcards

1
Q

What is the classification of Bactrim?

A

Bactrim is classified as a combination antibiotic, specifically a sulfonamide.

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2
Q

What are the active ingredients in Bactrim?

A

The active ingredients in Bactrim are sulfamethoxazole and trimethoprim.

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3
Q

What is the typical adult dosage of Bactrim for treating infections?

A

The typical adult dosage of Bactrim is one double-strength tablet (800 mg sulfamethoxazole and 160 mg trimethoprim) every 12 hours.

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4
Q

What is the mechanism of action of Bactrim?

A

Bactrim works by inhibiting bacterial folic acid synthesis, which is crucial for DNA and RNA production.

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5
Q

Which types of infections is Bactrim commonly indicated for?

A

Bactrim is commonly indicated for urinary tract infections, respiratory infections, and certain types of gastroenteritis.

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6
Q

True or False: Bactrim can be used to treat viral infections.

A

False.

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7
Q

What is a common adverse effect of Bactrim?

A

A common adverse effect of Bactrim is gastrointestinal upset, including nausea and vomiting.

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8
Q

What serious adverse effect is associated with Bactrim?

A

A serious adverse effect associated with Bactrim is Stevens-Johnson syndrome.

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9
Q

Fill in the blank: Bactrim can interact with ________ medications, increasing the risk of toxicity.

A

warfarin

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10
Q

What should be monitored in patients taking Bactrim?

A

Renal function should be monitored in patients taking Bactrim.

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11
Q

True or False: Bactrim is safe for use in pregnant women.

A

False.

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12
Q

Which laboratory test may be affected by Bactrim?

A

Bactrim may affect the results of potassium levels, leading to hyperkalemia.

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13
Q

What is the pediatric dosage of Bactrim for children older than 2 months?

A

The pediatric dosage of Bactrim is typically 8-12 mg/kg/day of trimethoprim component, divided into two doses.

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14
Q

True or False: Bactrim can be used to treat fungal infections.

A

False.

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15
Q

What is the risk of using Bactrim in patients with a history of sulfa allergy?

A

Patients with a history of sulfa allergy may experience allergic reactions and should avoid Bactrim.

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16
Q

What should be considered before prescribing Bactrim to elderly patients?

A

Elderly patients may have decreased renal function, requiring dosage adjustments.

17
Q

What type of bacteria does Bactrim primarily target?

A

Bactrim primarily targets gram-positive and gram-negative bacteria.

18
Q

Fill in the blank: Bactrim is contraindicated in patients with a history of ________.

A

blood dyscrasias

19
Q

What is a key consideration when prescribing Bactrim in relation to hydration?

A

Patients should be encouraged to maintain adequate hydration to prevent crystalluria.

20
Q

What is the route of administration for Bactrim?

A

Bactrim is administered orally.

21
Q

True or False: Bactrim can be used to treat infections caused by MRSA.

A

True, but it is not the first-line treatment.

22
Q

What is the effect of Bactrim on folate levels?

A

Bactrim can decrease folate levels, leading to potential deficiencies.

23
Q

What should be done if a patient experiences a rash while taking Bactrim?

A

The medication should be discontinued immediately.

24
Q

Fill in the blank: Bactrim is not recommended for use in ________ patients due to potential renal side effects.

A

dehydrated

25
What is a potential interaction between Bactrim and diuretics?
Bactrim may increase the risk of hyperkalemia when used with potassium-sparing diuretics.
26
What should be assessed before starting Bactrim therapy?
A thorough medication history and assessment for allergies should be conducted.