Rosuvastatin Flashcards
What is the classification of Rosuvastatin?
Rosuvastatin is classified as a statin, specifically an HMG-CoA reductase inhibitor.
What is the primary action of Rosuvastatin?
The primary action of Rosuvastatin is to lower cholesterol levels by inhibiting the enzyme HMG-CoA reductase.
What is the usual starting dosage of Rosuvastatin for adults?
The usual starting dosage of Rosuvastatin for adults is 10 mg once daily.
True or False: Rosuvastatin can be used to reduce the risk of cardiovascular events.
True
Fill in the blank: Rosuvastatin is indicated for the treatment of _______.
hyperlipidemia
What are common adverse effects of Rosuvastatin?
Common adverse effects include headache, myalgia, and gastrointestinal disturbances.
What is a serious adverse effect associated with Rosuvastatin?
Rhabdomyolysis is a serious adverse effect associated with Rosuvastatin.
Which of the following is a potential drug interaction with Rosuvastatin? A) Antacids B) Warfarin C) Grapefruit juice
C) Grapefruit juice
True or False: Rosuvastatin is contraindicated in patients with active liver disease.
True
What should be monitored regularly in patients taking Rosuvastatin?
Liver function tests and lipid levels should be monitored regularly.
What is the maximum recommended dose of Rosuvastatin in adults?
The maximum recommended dose of Rosuvastatin is 40 mg once daily.
Which patient population should use caution when prescribed Rosuvastatin?
Elderly patients should use caution when prescribed Rosuvastatin.
What lifestyle modifications should accompany Rosuvastatin therapy?
Dietary changes and increased physical activity should accompany Rosuvastatin therapy.
Fill in the blank: Rosuvastatin is primarily metabolized by _______.
the liver
What is the effect of combining Rosuvastatin with fibrates?
The combination may increase the risk of muscle-related side effects.
True or False: Rosuvastatin is effective in lowering LDL cholesterol levels.
True
What is the mechanism of action of Rosuvastatin?
Rosuvastatin works by inhibiting the enzyme responsible for cholesterol synthesis in the liver.
What are the indications for prescribing Rosuvastatin?
Indications include hyperlipidemia, prevention of cardiovascular disease, and familial hypercholesterolemia.
Which monitoring parameter is crucial for assessing the safety of Rosuvastatin?
Creatine kinase levels should be assessed to monitor for muscle damage.
Fill in the blank: Rosuvastatin can cause an increase in _______ levels.
transaminase
What is the initial dose adjustment recommendation for patients with renal impairment taking Rosuvastatin?
The initial dose should be reduced to 5 mg in patients with moderate renal impairment.
True or False: Rosuvastatin should be taken at any time of day, with or without food.
True
What is the primary benefit of Rosuvastatin therapy?
The primary benefit is the reduction of LDL cholesterol and overall cardiovascular risk.
When should Rosuvastatin be discontinued?
Rosuvastatin should be discontinued if there are signs of severe muscle pain or weakness.
