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Biochemistry > Vitamin B6 (Pyridoxine) > Flashcards

Vitamin B6 (Pyridoxine) Flashcards

1
Q

Active form of Pyridoxine

A

Pyridoxal phosphate (PLP) - Mainly used for AMINO ACID METABOLISM

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2
Q

Coenzyme Role of Pyridoxal PLP

A

Transamination

Decarboxylation of amino acids

Transulfuration

Tryptophan metabolism - coenzyme of KYNURENISE involved in synthesis of niacin from Tryptophan

Heme synthesis - ALA SYNTHASE

Glycogenolysis - GLYCOGEN PHOSPHORYLASE

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3
Q

Deficiency of Vitamin B6 (Pyridoxine)

A

MICROCYTIC HYPOCHROMIC ANEMIA
Sideroblastic anemia
Pellagra like symptoms

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4
Q

Drugs that interact w/ carbonyl group and causes PLP deficiencies

A

L-Dopa
Penicillamine
Cycloserine

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5
Q

High Doses of Pyridoxine given in

A

Carpal Tunnel Syndrome
Premenstrual Syndrome
Schizophrenia
Diabetic neuropathy

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6
Q

Important in STEROID HORMONE action

A

Vitamin B6 (Pyridoxine)

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7
Q

Excess of Vitamin B6 (Pyridoxine)

A

SENSORY NEUROPATHY

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Biochemistry (75 decks)

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