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Biochemistry > Topnotch Final Exam > Flashcards

Topnotch Final Exam Flashcards

1
Q

Essential AA

A

NOT synthesized by the body
PVT TIM HaLL

Phenyalanine
Valine
Tryptophan
Threonine
Isoleucine
Methionine
Histidine
Leucine
Lysine
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2
Q

Semi Essential AA

A

Conditionally essential
needed in extra amount during GROWTH and DEVT of CHILDREN

Arginine

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3
Q

Non Essential AA

A

Synthesized by the body

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4
Q 
skeletal changes
vascular changes
ectopic lens (upward, outward)

FIBRILLIN - scaffold for elastin synthesis

A

Marfan Syndrome (AD)

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5
Q

hyperextensible skin
hypermobille joint
easy bruisability

COLLAGEN (type III - MC affected)

A

Ehlers Danlos Syndrome (AD)

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6
Q

Villefranche Classification of Ehlers Danlos Syndrome

HYPERMOBILITY

A

Type III collagen
Tenascin X

MC subtype

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7
Q

Villefranche Classification of Ehlers Danlos Syndrome

CLASSICAL

A

Type V collagen

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8
Q

Villefranche Classification of Ehlers Danlos Syndrome

VASCULAR

A

Type III collagen

deadliest; most lethal

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9
Q

Villefranche Classification of Ehlers Danlos Syndrome

KYPHOSCOLIOSIS

A

Lysylhydroxylase

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10
Q

Villefranche Classification of Ehlers Danlos Syndrome

ARTHROCHALASIS

A

Type I collagen

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11
Q

Villefranche Classification of Ehlers Danlos Syndrome

DERMATOSPARAXIS

A

ADAMTS2

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12
Q

IMPORTANT GAGs

cell migration during morphogenesis and repair

A

Hyaluronic Acid

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13
Q

IMPORTANT GAGs

major component of CARTILAGE

A

Chondroitin sulfate

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14
Q

IMPORTANT GAGs

isolated in CORNEA

A

Keratan sulfate I

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15
Q

IMPORTANT GAGs

isolated in CARTILAGE

A

Keratan sulfate II

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16
Q

IMPORTANT GAGs

anticoagulant
found mainly in MAST CELLS

A

Heparin

17
Q

IMPORTANT GAGs

found in KIDNEY BASEMENT MEMBRANE along w/ TYPE IV collagen

A

Heparan sulfate

18
Q

IMPORTANT GAGs

main GAG of the SKIN

A

Dermatan

19
Q

IMPORTANT GAGs

most ABUNDANT GAG in BODY

A

Chondroitin sulfate

20
Q

Pentose Phosphate Pathway

LOCATION

A

Cytosol

21
Q

Pentose Phosphate Pathway

RATE LIMITING STEP

A

G6P dehydrogenase

22
Q

Pentose Phosphate Pathway

ATP USED/FORMED

A

NONE

23
Q

Pentose Phosphate Pathway

GOALS

A

source of NADPH (for reduction)

generate PENTOSES

24
Q

Pentose Phosphate Pathway

LOCATION IN THE BODY

A

RBC, lens

liver, adipose tissue, adrenal cortex, gonads, lactating mammary glands

25
Q

MC red cell enzyme abnormality causing hemolysis

A

G6PF deficiency (XR)

2nd MC - Pyruvate Kinase deficiency (AR)

26
Q

Electrophoretic Separation of Lipoproteins

A

chylomicron – LDL – VLDL – HDL

27
Q

Comparative Sizes of Lipoproteins

A

chylomicron – VLDL – IDL – LDL– HDL

28
Q

Ultracentrifugation of Lipoproteins

A

chylomicron – VLDL – LDL– HDL

Biochemistry (75 decks)

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