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Biochemistry > Purine Metabolism > Flashcards

Purine Metabolism Flashcards

1
Q

Rate limiting steps of Purine metabolism

A

Glutamine PPRP amidotransferase

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2
Q

STEPS

A 
ribose-5-phosphate
PRPP
IMP
Adenylosuccinate -> AMP -> ADP -> ATP
Xanthosine monophosphate (XMP) -> GMP -> GDP -> GTP
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3
Q

Drugs that act on purine synthesis

A

Ribavirin

Mycophenolate mofetil

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4
Q

Converts ADP and GDP to dADP and dGDP

A

ribonucleotide reductase

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