Lipoproteins Flashcards
LARGEST DIAMETER
lowest density
highest TAG content
CHYLOMICRON
Chylomicron
intestines
dietary TG –> peripheral tissues
cholesterol –> liver
apo B48
apo CI, CII, CIII
apo E
apo AI, AII, AIV
VLDL
liver
hepatic TG –> peripheral tissues
apo B100
apo CI, CII, CIII
apo E
From degradation of VLDL
IDL (VLDL remnant)
apo B100
apo E
IDL
TG and cholesterol –> liver
Maximum cholesterol
70% of LDL - liver
30% - extrahepatic tissues
LDL
LDL
from IDL
cholesterol and cholesterol ester –> extrahepatic tissues and liver
apo B100
Acts as repository for apo C and apo E required for metabolic of VLDL and chylomicrons
HDL
HDL
peripheral tissue cholesterol –> liver
REVERSE CHOLESTEROL TRANSPORT
apo AI, AII, AI2
apo CI, CII, CIII
apo D and E