Ketogenesis Flashcards
1
Q
Synthesis of ketone bodies which serve as alternative for peripheral tissues
A
KETOGENESIS
2
Q
Site of ketogenesis
A
LIVER
MITOCHONDRIA
3
Q
Substrate for Ketogenesis
A
Acetyl CoA
4
Q
Products of Ketogenesis
A
ACETOACETATE
B-HYDROXYBUTYRATE
ACETONE
5
Q
Rate Limiting Step of Ketogenesis
A
Acetoacetyl CoA + Acetyl CoA –> HMG CoA
HMG COA SYNTHASE
6
Q
Produced ATP when acetoacetate is the end product
A
26 mol of ATP
7
Q
Produced ATP when B-hydroxybutyrate is the end product
A
21 mol of ATP
8
Q
Primary Ketone Body
A
Acetoacetate
9
Q
Secondary Ketone Bodies
A
Acetone
Beta Hydroxybutyrate
10
Q
Neutral Ketone Body
A
Acetone
11
Q
Ketone body excreted through lungs
A
Acetone
12
Q
Site of synthesis of ketone bodies
A
Liver Mitochondria