Glycogenesis (Glycogen Synthesis)

Question 1

Major storage carbohydrate in animals

Branched polymer of a-D-glucose

Answer 1

GLYCOGEN

~500 g stored in muscle and liver

a 1,4 linkage - UNBRANCHED
a 1,6 linkage - BRANCHED

Question 2

For synthesis of glycogen

Answer 2

Glycogenesis

Question 3

Site of Glycogenesis

Answer 3

Liver and Muscle

CYTOSOL

Question 4

Substrate of Glycogenesis

Answer 4

a-D glucose

Question 5

Product of Glycogenesis

Answer 5

Glycogen

Question 6

Rate Limiting Step of Glycogenesis

Answer 6

Elongation of glycogen chains (creation of a 1,4 glycosidic bonds)

GLYCOGEN SYNTHASE

Question 7

Contributes to blood glucose

Answer 7

Liver Glycogen

Question 8

Serves as a source of energy to muscle itself

Does NOT directly contribute to blood glucose

Answer 8

Muscle Glycogen

Question 9

Protein that serves as a PRIMER for glycogen synthesis when glycogen is completely depleted

Answer 9

GLYCOGENIN

Question 10

Synthesis of UDP glucose

Answer 10

a-D glucose is attached to uridine diphosphate and this becomes the source of all glucosyl residues that are added to the glycogen molecule

PHOSPHOGLUCOMUTASE and UDP GLUCOSE PHOSPHORYLASE