Uronic Acid Pathway Flashcards
1
Q
An alternative pathway for glucose
Does NOT produce ATP
A
Uronic Acid Pathway
2
Q
Site of Uronic Acid Pathway
A
LIVER
CYTOSOL
3
Q
Biochemical Role of Uronic Acid Pathway
A
To produce Glucoronic Acid
To produce Ascorbic Acid
- but NOT in higher primates and mammals
- LACK L-GULONOLACTONE OXIDASE
To produce pentoses
4
Q
Essential component of glycosaminoglycans (GAG)
A
Glucuronic Acid
required in detoxification reactions of insoluble compounds
- bilirubin
- steroids
- morphine and other drugs
5
Q
This enzyme is absent in primates and guinea pigs
In these animals ascorbic acid is an essential vitamin in the diet
A
L-GULONOLACTONE OXIDASE
6
Q
Increased xylulose in the urine d.t. deficiency of xylulose reductase
A
Essential Pentosuria
XYLULOSE REDUCTASE DEFICIENCY