Uronic Acid Pathway Flashcards

1
Q

An alternative pathway for glucose

Does NOT produce ATP

A

Uronic Acid Pathway

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2
Q

Site of Uronic Acid Pathway

A

LIVER

CYTOSOL

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3
Q

Biochemical Role of Uronic Acid Pathway

A

To produce Glucoronic Acid

To produce Ascorbic Acid

  • but NOT in higher primates and mammals
  • LACK L-GULONOLACTONE OXIDASE

To produce pentoses

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4
Q

Essential component of glycosaminoglycans (GAG)

A

Glucuronic Acid

required in detoxification reactions of insoluble compounds

  • bilirubin
  • steroids
  • morphine and other drugs
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5
Q

This enzyme is absent in primates and guinea pigs

In these animals ascorbic acid is an essential vitamin in the diet

A

L-GULONOLACTONE OXIDASE

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6
Q

Increased xylulose in the urine d.t. deficiency of xylulose reductase

A

Essential Pentosuria

XYLULOSE REDUCTASE DEFICIENCY

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