Varicella Flashcards

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1
Q

Varicella known as chickenpox

vaih re cha La

vari ce lla

A

an acute infectious disease

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2
Q

Signs and Symptoms

A

early:
(1) fever
(2) headache
(3) malaise
then
1-rash begins 10-21 days after infection as small, red spots
2-become little bumps
3-then small fluid-filled blisters
then
lesions can erupt anywhere on the body

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3
Q

-rash begins 10-21 days after infection as small, red spots

A

macules

mac yil

mac ules بقع

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4
Q

become little bumps

A

papules

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5
Q

small fluid-filled blisters

A

vesicles/pustules

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6
Q

at increased risk :

A

(1) more severe in older children & adults
(2) threat to immunocompromised people and
also rash can spread over whole body

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7
Q

chracteristic :

A

1-most cases mild
2-begins with pain or tingling in skin
supplied by sensory nerve with latent virus
3-major threat to babies

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8
Q

lesions usually 1st appear on:

A
  • head
  • chest
  • back
    -on mucous membranes
    -itch
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9
Q

_______________can lead to serious secondary infections

A

scratching

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10
Q

Causative Agent

A

Varicella-zoster virus (VZV)
Zoster = shingles

zas tir/shin gils

zoster/ shin gle

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11
Q

reactivation of own latent virus
اعادة تنشيط الفيروس الكامن الخاص

A

(1) can occur at any age
(2) increasingly common later in life
(3) does not spread person to person

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12
Q

rash similar to chickenpox except:

A

(1) limited to one side of the body
(2) painful

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13
Q

duration of pain :

A

-lesions subside in week
-pain can last months or longer

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14
Q

transmission:

A

(1) result in chickenpox in susceptible person
(2) need contact with drainage from lesions

sis sap tib ill=vulnerable=قابل للعطب

sus cep tible

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15
Q

Pathogenesis

A

-enters body by respiratory route
-disseminates to skin via bloodstream

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16
Q

Epidemiology

A

human only reservoir
highly contagious
infectious 1-2 days before rash until all lesions crusted over (~4 days after onset)

17
Q

peak incidence

A

winter & spring

18
Q

congenital varicella syndrome can cause:

A

(a) underdeveloped head & limbs
(b) cataracts
case-fatality rate up to 30% in newborns

19
Q

Prevention

A

vaccine for chickenpox
(single agent or MMRV)
50+ vaccine for shingles

20
Q

Treatment:

A

acyclovir & famciclovir

a sik liv eer/ fm sik liv eer

a cyclo vir / fam cic lovir

21
Q

An area of abnormal or damaged tissue caused by injury, infection, or disease

A

lesions جرح

lee jin

le sion

22
Q
A