Streptococcal Pharyngitis/Strep Throat Flashcards
Streptococcal Pharyngitis/Strep Throat
definition?
S trap tik ka kill fair n ji tis / s trap throat
strep to coc cal pharyn gitis / step throat
an infection in the throat and tonsils caused by bacteria called group A Streptococcu
Signs and Symptoms
1-sore throat
2-difficult swallowing
3-fever
4- redness of throat
5-patches of adhering pus
6- scattered tiny hemorrhages
نزيف
7-enlarged and tender lymph node in neck
8-older children & young adults: may have abdominal pain or headache
S wallo wing / pa tchs / s ka tired tiny /ham rig is /tn dir
swallowing / patches / scatter ed / hemo rr hages /tender
Causative Agent
Streptococcus pyogenes
a major human-specific bacterial pathogen
s trap tikko kiss / pa ya gin ees
streptococus py o genes
Epidemiology
1-spread easily by respiratory droplets
2- carriers
peak incidence :
highest incidence :
1-winter or spring
2- grade school children
Prevention
adequate ventilation
avoid crowded situation
aad iq wint van till ation
ad equate / vent il ation
Treatment
antibiotics
pathogenosis
1-Attachment to host cell via Fibronectin-binding proteins
2-inactive complement component via M protein
2-interferes with phagocytosis via M protein
3- inhibits phagocytosis via capsule
3- composed of hyaluronic acid via capsule
4-enhance spread via tissue-degrading enzymes
5-lyse RBCs and WBCs via Streptolysins O and S
fi bro nk tin biding protein / hi lir aa nik / strap to li sins
fibro nec tin / hy al u ronic / strep to lysins
Attachment to host cell via
Fibronectin-binding proteins
1-inactive complement component
2-interferes with phagocytosis
M protein
(1) inhibits phagocytosis
(2) composed of hyaluronic acid
capsule
(a) Normal components of human tissue
(b) difficult for immune system to detect
hyaluronic acid
enhance spread
tissue-degrading enzymes
lyse RBCs and WBCs
Streptolysins O and S
