Inhalation anthrax Flashcards
Inhalation Anthrax
N hell ation anth rax
inhalation an thrax
develops when you breathe in anthrax spores
Signs and Symptoms
flu-like symptoms:
(1) discomfort
(2) mild fever
(3) nonproductive cough
b. shortness of breath
c. chest pain
d. can lead to cyanosis
half cases symptoms :
anthrax meningitis
Causative Agent
Bacillus anthracis
bis ill s an thra sis
bac ill us an thra cis
epidemiology
1-case-fatality rate without treatment ~95%; with treatment ~45%
2-b. No person to person spread
3- potential agent for bioterrorism
4-extremely rare in us
5-zoonotic disease
can be transmitted to humans who work with animals or animal products
zoonotic disease
zwin aa tic
zoo notic
zoonotic disease happen usually
slaughterhouse workers=مسلخ
leather tanneries
la thir tan ir ees / s latir
leather tanner ies / slaughter
pathogenosis
1-endospores taken up by alveolar macrophages
carried to chest lymph node then germinate
2-toxin
(1) kill phagocytes
(2) damage surrounding tissue
germ n ate =ينبت او يتبرعم
germ in ate
Prevention
1-attenuated vaccine for livestock
2-subunit vaccine for
- military
- lab workers
- handlers of certain animals/animal products
Treatment
1-Need to be prompt
2- mechanical ventilation
3- drainage of fluid from lungs
4- antimicrobial medications
5-monoclonal Ab (binds to component of toxin)
drain ij / moh noh clohn ill
mono clonal