Helicobacter pylori Gastritis Flashcards
Helicobacter pylori Gastritis
ha lik oo bac tr/ py lohr i / gas tri tis
he lico bacter
(H. pylori) is a type of bacteria that causes infection in the stomach.
It is the main cause of peptic ulcers, and it can also cause gastritis and stomach cancer
. About 30 to 40% of people in the United States get an H. pylori infection
Signs and Symptoms
most asymptomatic
gastritis signs :
(1) belching
(2) bloating
(3) loss of appetite
(4) nausea
(5) sometimes vomiting
(1) التجشؤ
(2) الانتفاخ
(3) فقدان الشهية
(4) الغثيان
(5) القيء أحياناً
bal ching=تجشو/blow tin=انتفاخ/ naz ya غثيان
bel ching/bloating/ na use a
peptic ulcer development :
1-localized abdominal pain
2-tenderness
3-bleeding
Causative Agent
Helicobacter pylori
pathogenosis
1-survives acidity of stomach by
-urease
-flagella
2-thinning of mucus layer
3-chronic gastritis
urease :
u re ais
u re ase
1- enzymes
2- converts urea into ammonia: creates alkaline microenvironment
flagella
flij aal la
flag ella
burrow within mucus layer coating stomach lining
bir oo=يسكن او يلجا
burrow
chronic gastritis can lead to __________
stomach cancer
Treatment
1-antibiotics
2- medication to inhibit stomach acid production
characteristic
1- probably fecal-oral route; possibly oral-oral
2- incidence increase with age
3-tend to cluster in families
ik less tir=تجمع او تكتل
cluster