Oral Herpes

Question 1

Oral Herpes known as : cold sores
and herpes labialis

Answer 1

an infection of the lips, mouth, or gums due to the herpes simplex virus.
It causes small, painful blisters commonly called cold sores or fever blisters

Question 2

Signs and Symptoms

Answer 2

1- often asymptomatic
2- fever
3- sore throat
4-headache
5-enlarged lymph nodes
6-small blisters or sores develop in throat, around mouth, or on lips
7-lesions typically heal without treatment within 14 days

Question 3

symptoms in case of recurrences :

Answer 3

1-usually less severe
2-more localized: itching , tingling , burning on lips
3-outbreak of blisters that break
(usually heal within 7-10 days)

Question 4

small blisters or sores :

Answer 4

1-blisters break within day or two
2-superficial ulcers that can be so painful can be difficult to eat or drink

Question 5

lesions

Answer 5

1- virus persists as latent infection
2-affected person may suffer recurrent cold sores

Question 6

Causative Agent :

Answer 6

Herpes Simplex Virus Type 1 (HSV-1)

Question 7

Pathogenesis

Answer 7

1-multiplies in epithelium of mouth or throat
2-cell destruction
3-formation of blisters containing large numbers of infectious virus
4-Immune response quickly limits infection
5-persists in nerve cell in latent form

Question 8

persists in nerve cell in latent form :

Answer 8

(1) can reactivate
(2) non-infectious & non-replicating

Question 9

transmission :

Answer 9

(1) primary by close physical contact
(2) fomites

Question 10

greatest risk :

Answer 10

1-contact with lesions or saliva within few days of disease onset
2-saliva of asymptomatic people often infectious

Question 11

Prevention :

Answer 11

1-sunscreen (sunlight can trigger recurrences)
2- acyclovir

Question 12

Treatment :

Answer 12

acyclovir

Question 13

acyclovir :

Answer 13

-for severe cases & prevent recurrences
-does NOT affect latent virus Not curative

Question 14

characteristic :

Answer 14

1/3 Americans