Diphtheria Flashcards

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1
Q

Diphtheria

dip theer ya

di ph ther ia

A

a serious infection caused by strains of bacteria

It can lead to difficulty breathing, heart rhythm problems, and even death.

CDC recommends vaccines for infants, children, teens, and adults to prevent diphtheria

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2
Q

Signs and Symptoms

A

(1) mild sore throat
(2) slight fever
(3) malaise (general discomfort)
(4) extreme fatigue

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3
Q

severe cases symptoms :

A

dramatic swelling of lymph nodes & surrounding neck tissue =bull-neck

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4
Q

many cases symptoms :

A

whitish-gray pseudomembrane (dead epithelial cells, clotted blood, WBCs) forms on:
(1) tonsil / throat OR
(2) in nasel cavity

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5
Q

later can cause

A

(1) heart failure
(2) kidney failure
(3)paralysis

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6
Q

Causative Agent

A

Corynebacterium diphtheriae

kor nee bac tear yim dip theer yay

coryne bacterium

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7
Q

Epidemiology

A

spread by air from infected people
(1) inhalation
(2) fomites
human primary reservior

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8
Q

Prevention

A

DTaP
(Diphtheria, Tetanus, Pertussis) VIS or vaccine information statement

ta tin is / prit o sis

diphtheria / tet anus / pert us sis

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9
Q

Treatment

A

antiserum against toxin
(1) done immediately
(2) potent toxin : daleying treatment can be fatal
b. antibiotics to prevent transmission
(1) no effect on absorbed toxin

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10
Q

Pathogenesis

A

1-little invasive ability (rarely enters blood or tissues)
2-exotoxin
(1) released by bacteria by growing in throat
(2)A-B Toxin
(3) can be absorbed by blood causing damage to:
(a) heart
(b) Nerve
(c) Kidney
3-membrane may come loose
(1) obstruct airway
(2) cause suffocation

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11
Q

incubation period

A

2-6

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