Pseudomonas aeruginosa Infections Flashcards
signs and symptoms :
a. green pus caused by bacterial pigments
b. often invades bloodstream causing:
(1) chills
(2) fever
(3) skin lesions
(4) shock
Leeh sion=جرح
le sion
Causative Agent
Pseudomonas aeruginosa
soo doh moh nis / air ign o sa
pse udo mon as/ ae rug in osa
Pathogenesis
1-infection of burns & other wounds
2-pili & flagellum
- attachment
- colonization
3-exoenzyme S
induces apoptosis of host cells
4-phospholipase C
- destroys lecithin
-important lipid component of cell membrane
-membrane destruction & cell death
5-exotoxin A
-stops host cell protein synthesis then death of cell
6-creates slime layer that promotes biofilm
fas fo lie pase/ less ith N
phos pho lipase /lec ithin
Prevention
prompt care of wounds
burn wounds
(1)careful removal of dead tissue
(2) application of antibacterial cream
Treatment
1-antibiotics (resistance an issue)
2-IV antibiotics at high doses for systemic infection
characteristic :
a. widespread in nature, carried on vegetation
b. opportunistic pathogen
c. major cause of nosocomial infections
d. can grow where there is moisture:
va jit a tion=حياة نباتيه/na so kom yil/
vege ta tion/ noso comial/
can grow where there is moisture :
soaps
cosmetics
swimming pools
hot tubs
contact lens solution
distilled water
disinfectants
الصابون
مستحضرات التجميل
حوض سباحة
أحواض المياه الساخنة
محلول العدسات اللاصقة
ماء مقطرة
المطهرات
coz ma tiks/ hat tb/ dis N fac tnt
cosmetics/ hot tubs / dis infectant