Rocky Mountain Spotted Fever Flashcards
Rocky Mountain spotted fever known as (RMSF)
is a bacterial disease spread through the bite of an infected tick
Signs and Symptoms
begins with:
(1) headache
(2) fever
(3) muscle , joint pain
signs and symptoms
1-few days after onset of fever, maculopapular rash with flat pink spots appear on ankles & wrists then spreads
2-may be followed by petechiae
3-without treatment, heart & kidney involvement
few days after onset of fever, maculopapular rash with flat pink spots appear on ankles & wrists then spreads :
makyil o papular
maculo papular rash
(1) to plams & soles
(2) up arms & legs to rest of the body
form when small vessels bleed under the skin
petechiae
round red spots under the skin caused by bleeding
pa teek ya
pe tech iae
without treatment, heart & kidney involvement, can cause:
(1) drop in BP
(2) shock
(3) death
Causative Agent
Rickettsia rickettsii
rikat ce ya rik it ce
rick e tt sia / rick e tt sii
Pathogenesis
1-released into capillary blood with tick saliva
2-damages host cell membrane
3-infection can spread into walls of small vessels
4-severe cases release endotoxin (LPS)
tick saliva
(1) bite painless & goes unnoticed
(2) tick feeds for hours
(3) not transmitted until 4-10 hours of feeding
damages host cell membrane which means _______________
cell ruptures
releases organisms
infection can spread into walls of small vessels then ?
(1) inflammation
(2) clotting
(3) necrosis
(4) hemorrhagic skin rash
him ir aa gik /
hemo rr h age /
severe cases release endotoxin (LPS)
leads to :
-shock
-clotting throughout body
disseminated intravascular coagulation (DIC)
التخثر المنتشر داخل الأوعية (DIC)
dis aamin a ted coo wag u lation
coa gulation
is a rare but serious condition that causes abnormal blood clotting throughout the body’s blood vessels
transmission
1-zoonosis
2-humans accidental host will be severe disease
3-tick infected then transmits to next generation through their eggs
zawin o sis/
zoon osis
little or no disease in natural host
balanced pathogenicity
