Study Guide 2 Flashcards
What are the types of OP?
- Primary
- Secondary
- Transient OP of the hip
What is primary OP?
- deterioration of bone mass, unassociated with other chronic illnesses or disease
- usu related to aging or menopause
- systemic, bilateral
What is secondary OP?
OP caused by metabolic or endocrine disorders
Transient OP of the hip:
- Onset
- Who gets it
- rare, idiopathic, transitory
- seen most commonly in middle aged men and pregnant women
What is osteomalacia?
Softening of the bones
What causes osteomalacia?
- Vit D deficiency
- lack of exposure to UV rays
Ability to synthesize Vit D and age
Ability to synthesize Vit D through sunlight diminishes after age 40
Osteomalacia: Looser’s transformation zones
Pseudofractures in areas of demineralization
“Rickets” in children usually due to
Malnutrition
What is rickets?
- causes bowing in the long bones
- due to malformation with epiphyseal plates
What is Paget’s disease?
Disordered bone modeling caused by
- genetic factors
- viral infection
What happens to the bones with Paget’s disease?
- produces larger, but weaker bones
- increased fx risk, deformity
Which bones are affected with Paget’s disease?
Specific area, not systemic
- pelvis
- spine
- skull
- tibia
Who is most at risk for getting OP?
- Women
- Over 60
- Caucasian
What pharmacology is used to treat OP?
- Calcium supplements
- Vitamin D
- Bisphosphonates
- Estrogen therapy
