Sodium Valporate Flashcards
1
Q
Introduction
A
- Anticonvulsant that is used to treat epilepsy
2
Q
Pharmacodynamics
A
- Increase concentration of GABBA receptors in the brain, opening up Chlorine channels to hyperpolerise the cell.
- Decrease the activaty over the synapse, increases the action potential of the cell
- Exists as Valporate in the blood
3
Q
Pharmacokinetics
A
- Absorbtion GI tract
- Widely distributed
- Metabolised in the liver
- Eliminated renally