Adrenaline

Question 1

Introduction to the drug

Answer 1

• Its a sympathomimetic that stimulates bothe Alpha and Beta adrengic receptors
• Increases peripheral resistance and improves perfusion pressures
• is a chemical that narrows blood vessels and opens airways in the lungs

Question 2

Presentation of the drug

Answer 2

• Prefilled syringe containing 1mg adrenaline in 1ml (1:1000)
• Pre filled shrine containing 1mg adrenaline in 10ml (1:10000)

Question 3

Why would you prescribe the drug

Answer 3

• Cardiac Arrest
• Anaphalaxis
• Life threatening asthma

Question 4

Typical dose

Answer 4

Cardiac arrest Shockable Rhythm

• After 3rd Shock, then alternate shocks 5th, 7th etc
• 1:10000

Cardiac Arrest Non Shockable Rhythm

• Immediately then every 3-5 minutes after
• 1:10000

Anaphalaxis and Life Threatening Asthma

• 500mcg every 5minutes
• 1:1000

Question 5

Pharmacodynamics of the drug

Answer 5

• Its a sympathomimetic that stimulates bothe Alpha and Beta adrengic receptors
• Increases peripheral resistance and improves perfusion pressures
• Increases Cardiac output
• is a chemical that narrows blood vessels and opens airways in the lungs

Question 6

Side effects

Answer 6

• Severe Hypertension in pts on Beta blockers
• fast or pounding heartbeats;
• pale skin, sweating;
• nausea and vomiting;
• dizziness;
• weakness or tremors;
• throbbing headache; or
• feeling nervous, anxious, or fearful.

Question 7

Pharmacokinetics of the drug

Answer 7

• Rapid acting but short lived
• Distributed to the heart, spleen, adrenergic nerves
• Metabolised in the liver
• Excreted in urine