Atropine Flashcards
1
Q
Intoduction
A
- Anticholinergic antagonist, alkoloid that increases heart rate
- Can reverse the effects of vagel overdrive
- Increase the firing of the SA Node
- Enhances AV conduction
2
Q
Presentation
A
- Pre filled syringe 1mg/1ml
- Ampoule 600mcg /1ml
3
Q
Why would you give the drug
A
- Symptomatic bradycardia in the presence of these signs
- Absolute bradycardia <40 bpm
- Systolic BP below expected for age
- Paroxysmal ventricular arrthymias requing suppression
- Inadequate perfusion causing confusion
4
Q
Dose
A
- IV 12yr< 600mcg/ 1ml every 3-5mins, Max 3mg
5
Q
Pharmacodynamics
A
- Cholinergic receptor antagonist, inhibiting stimulation from the parasympathetic nerve by blocking effects of Acetylcholine
6
Q
Pharmacokinetics
A
- IV absorption
- Widely distributed
- Metabolised in the liver
- Eliminated renally
7
Q
Side effects
A
- Dry mouth, visual blurring
- Confusion
- Tachycardia
- Retenion of urine
