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Drugs > Diazepam > Flashcards

Diazepam Flashcards

1
Q

Introduction

A

Anticonvulsant - sedative

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2
Q

Pharmacodynamics

A
  • CNS depressant
  • Acts on agonising GABBA by opening the Chlorine channels in the cell, and repolerising it, reduces the excitability across the cells synapse.
  • Needs a greater Action Potential to fire of due to hyperpolerised cell
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3
Q

Pharmacokinetics

A
  • IV/PR
  • Widely Disributed
  • Hepactically
  • Eliminated Renally
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4
Q

Presentation

A
  • Ampoule 10mg/2ml

- Rectel Tube 2.5mg, 5mg, 10mg

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5
Q

Why would you give the drug

A
  • Fits longer then 5mins and still Fitting
  • Repeated Fits
  • Status epilepticus 30mins
  • Eclampic Fits
  • Cocaine systematic chest pain.
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6
Q

Dose

A
  • IV = 10mg/2ml repeated 10mg/2ml
  • Rectal = 20mg
  • Max 20mg
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7
Q

Side Effects

A
  • Resp Depression
  • Hypotension
  • Drowsiness
  • Confusion
  • Ammnesia
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Drugs (53 decks)

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