Ondansetron Flashcards

1
Q

Introduction

A
  • Antiemetic
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2
Q

Presentation

A
  • Amppoule 4mg in 2ml
  • 8mg in 4ml

(both 2mg in 1ml)

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3
Q

Why would you give this drug

A
  • Treatment of nausea and vomitting

- Prevention of nausea and vomitting for morphine administration

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4
Q

Dose

A
  • 4mg
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5
Q

Pharmacodynamics

A
  • 5HT3 (dopamine) recptor antagonist within the chemoreceptor trigger zone of the mid brain which inhibits the vomitting centre
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6
Q

Pharmacokinetics

A
  • IV/IM administration
  • Widley distributed
  • Metabolised hepatic ally
  • Eliminated renally
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7
Q

Side Effects

A
  • Hiccups
  • Constipation
  • Flushing
  • Hypotension
  • Chest Pain
  • Arrhythmias
  • Bradycardia
  • Headache
  • Seizures
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