Ondansetron Flashcards
1
Q
Introduction
A
- Antiemetic
2
Q
Presentation
A
- Amppoule 4mg in 2ml
- 8mg in 4ml
(both 2mg in 1ml)
3
Q
Why would you give this drug
A
- Treatment of nausea and vomitting
- Prevention of nausea and vomitting for morphine administration
4
Q
Dose
A
- 4mg
5
Q
Pharmacodynamics
A
- 5HT3 (dopamine) recptor antagonist within the chemoreceptor trigger zone of the mid brain which inhibits the vomitting centre
6
Q
Pharmacokinetics
A
- IV/IM administration
- Widley distributed
- Metabolised hepatic ally
- Eliminated renally
7
Q
Side Effects
A
- Hiccups
- Constipation
- Flushing
- Hypotension
- Chest Pain
- Arrhythmias
- Bradycardia
- Headache
- Seizures