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Drugs > Midazalam > Flashcards

Midazalam Flashcards

1
Q

Introduction

A

Benzodiazepine - Short acting CNS depressant

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2
Q

Pharmacodynamics

A
  • Binds to GABBA receptors in the brain
  • Gabba angonist, opens the Chlorine channel which hyperpolerises the cell, this makes the cell less likely to fire off.
  • Needs more Action potential to fire
  • Dampen downs the sending of the signal
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3
Q

Pharmacokinetics

A
  • GI absorption
  • CNS distribution
  • Metabolised in the Liver
  • Eliminated Renally
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4
Q

Presentation

A

Ampoules 5ml, 10mg/1ml

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5
Q

Why would you prescribe the drug

A
  • Convulsant 5mins and still fitting
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6
Q

Dose

A
  • Tailored dose to each patient
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7
Q

Side Effects

A
  • Resp depression
  • Hypotension
  • Drowsiness
  • Muscle Weakness
  • Slurred Speech
  • Agitation
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Drugs (53 decks)

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