Metformin

Question 1

Introduction

Answer 1

• Antihyperglyceamic

- Used to treat NIDDM

Question 2

Pharmacodynamics

Answer 2

• Its a Biguanide which acts by reducing the synthesis of glucose in the liver and causes a reduced secretion of glucose into the plasma, it reduces glucose absorption into the in]testine
• Lowers Plasma Triglyceride levels

Question 3

Pharmacokenitcs

Answer 3

• Oral
• Widely
• Not Metabolised
• Urine