Benzylpenicillin Flashcards
1
Q
Introduction to the drug
A
Benzylpenicillin, also known as penicillin G, is an antibiotic used to treat a number of bacterial infections.
2
Q
Presentation of the drug
A
- Ampoule 600mg as powder
- IM/IV
3
Q
Why would you administer the drug
A
- Meningococcal septiceamia
4
Q
Typical dose
A
Adult
- 1.2g dissolved in 19.2ml water foe injection = 20ml
5
Q
Pharmacodynamics of the drug
A
- Binds to specific penicillin binding proteins and inhibits synthesis of peptidoglycan in the cell wall
6
Q
Pharmacokinetics
A
- IV/IM absorption
- Distributed in the blood
- Metabolised hepatic ally
- Excreted renally
