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Pharm 233 > Respiratory drugs > Flashcards

Respiratory drugs Flashcards

1
Q

Salbutamol

A

Short acting B2 agonist
-dilate bronchi
-reduce, TNFa
—
-asthma PRN
—
-tachycardia
-tremor
-dysrhythmias

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2
Q

Terbutaline

A

Short acting B2 agonist
-dilate bronchi
-reduce, TNFa
—
-asthma PRN
—
-tachycardia
-tremor
-dysrhythmias

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3
Q

Salmeterol

A

Long acting B2 agonist
-dilate bronchi
-reduce, TNFa
—
-asthma BID 8-12h of action
—
-tachycardia
-tremor
-dysrhythmias

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4
Q

Formoterol

A

Long acting B2 agonist
-dilate bronchi
-reduce, TNFa
—
-asthma BID 8-12h of action
—
-tachycardia
-tremor
-dysrhythmias

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5
Q

Theophylline

A

Methylxanthine
-Bronchodilator by reducing Ca+
—
-Asthma
—
-dysrhythmia
-seizures

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6
Q

aminophylline

A

Methylxanthine
-Bronchodilator by reducing Ca+
—
-Asthma
—
-dysrhythmia
-seizures

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7
Q

Montelukast

A

bronchodilator
-antagonizes CysLT1 receptor cause dilation, reduce hyper response, reverse edema and hyper secretion
—
-asthma
—
-headache

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8
Q

Zafirlukast

A

bronchodilator
-antagonizes CysLT1 receptor cause dilation, reduce hyper response, reverse edema and hyper secretion
—
-asthma
—
-headache
-inhibits CYP3A4 (warfarin)

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9
Q

Beclometasone

A

Glucocorticoid
-Cause up/down regulation
-reduce IL-2/TNFa/IgE
-inhibit eosinophils by reducing IL-5, IL-13
-inhibit HTc
—
-asthma
—
-Thrush
-adrenal suppression

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10
Q

budenoside

A

Glucocorticoid
-Cause up/down regulation
-reduce IL-2/TNFa/IgE
-inhibit eosinophils by reducing IL-5, IL-13
-inhibit HTc
—
-asthma
—
-Thrush
-adrenal suppression

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11
Q

fluticasone

A

Glucocorticoid
-Cause up/down regulation
-reduce IL-2/TNFa/IgE
-inhibit eosinophils by reducing IL-5, IL-13
-inhibit HTc
—
-asthma
—
-Thrush

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12
Q

mometasone

A

Glucocorticoid
-Cause up/down regulation
-reduce IL-2/TNFa/IgE
-inhibit eosinophils by reducing IL-5, IL-13
-inhibit HTc
—
-asthma
—
-Thrush

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13
Q

ciclesonide

A

Glucocorticoid
-Cause up/down regulation
-reduce IL-2/TNFa/IgE
-inhibit eosinophils by reducing IL-5, IL-13
-inhibit HTc
—
-asthma
—
-Thrush

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14
Q

Omalizumab

A

/
Antibody against IgE (only binds free IgE)
—
-severe allergic asthma when GC fail
—
-anaphylaxis

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15
Q

Mepolizumab

A

/
antibodies against IL-5 which inhibits eosinophil differentiation and recruitment
—
-eosinophilic asthma
—
-headache

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16
Q

Reslizumab

A

/
antibodies against IL-5 which inhibits eosinophil differentiation and recruitment
—
-eosinophilic asthma
—
-headache

17
Q

Ipratropium

A

Non selective Anticholinergic
-M3/M1 block bronchodilates and reduces secretions
—
-COPD
—
-dry mouth
-nose bleeds)

18
Q

Tiotropium

A

Selective Anticholinergic
-M3 block bronchodilates and reduces secretions
—
-COPD
—
-dry mouth
-nose bleeds)

19
Q

Roflumilast

A

Long acting PDE4 inhibitor
-reduces inflammation
—
-COPD (used alongside dilators)
—
GI Sx

Pharm 233 (57 decks)

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