Anemia drugs

Question 1

Ferrous sulfate

Answer 1

Oral Hematinic iron
-gives iron
-highest elemental iron
——-
-iron deficiency
——
-GI upset

Question 2

Ferrous fumarate

Answer 2

Oral Hematinic iron
-gives iron
——-
-iron deficiency
——
-GI upset

Question 3

Ferrous gluconate

Answer 3

Oral Hematinic iron
-gives iron
——-
-iron deficiency
——
-GI upset

Question 4

Polysaccharide iron complex

Answer 4

Oral Hematinic iron
-gives iron
-Good for sensitive GI tracts
——-
-iron deficiency
——
-GI upset

Question 5

Iron dextran

Answer 5

IV Hematinic iron
-gives iron
——-
-iron deficiency
——
-GI upset

Question 6

Sodium ferric gluconate

Answer 6

IV Hematinic iron
-gives iron
——-
-iron deficiency
——
-GI upset

Question 7

Iron sucrose

Answer 7

IV Hematinic iron
-gives iron
-Low change for anayphylsis
——-
-iron deficiency
——
-GI upset

Question 8

Desferrioxamine

Answer 8

Iron chelator
-prevents iron overdose and toxicity
——
-can also be used for thalassaemia

Question 9

cyanocobalamin (B12)

Answer 9

needed for DNA synthesis
-deficiency leads to megaloblastemia
-can also strip nerves if deficient
——–
-pernicious anemia
-megaloblastic/ microcytic anemia
——-

Question 10

Hydroxocobalamin (B12)

Answer 10

needed for DNA synthesis
-deficiency leads to megaloblastemia
-can also strip nerves if deficient
——–
-pernicious anemia
-megaloblastic/ microcytic anemia
——-

Question 11

Folic acid (B9)

Answer 11

/
needed for DNA synthesis
——
-megaloblastic/macrocyti anemia
-proper neural tube development
-given with methotrexate
-pernicious anemia + B12

Question 12

Epoetin alfa or darbepoetin alfa

Answer 12

/
growth factor from kidneys acting in bone marrow
——-
-anemia
-renal failure anemia
-chemo anemia
——–
-low iron
-thrombosis (high hematocrit)
-HTN via AT II
-Seizures

Question 13

Filgrastim

Answer 13

Granulocyte Colony stimulating factor
-stimulate neutrophil production via JAK/STAT
——-
-chemo loss of immune cells
-severe neutropenia
-HIV
———
-bone loss
-renal failure
-lung damage
-splenic rupture
-sicle cell crises
-joint pain

Question 14

Lenograstim

Answer 14

Granulocyte Colony stimulating factor
-stimulate neutrophil production via JAK/STAT
——-
-chemo loss of immune cells
-severe neutropenia
-HIV
———
-bone loss
-renal failure
-lung damage
-splenic rupture
-sicle cell crises
-joint pain

Question 15

Pegfilgrastim

Answer 15

Granulocyte Colony stimulating factor
-stimulate neutrophil production via JAK/STAT
——-
-chemo loss of immune cells
-severe neutropenia
-HIV
———
-bone loss
-renal failure
-lung damage
-splenic rupture
-sicle cell crises
-joint pain

Question 16

Sargramostim

Answer 16

Granulocyte-monocyte Colony stimulating factor
-stimulate neutrophil production via JAK/STAT
——-
-chemo loss of immune cells
-severe neutropenia
-HIV
———
-bone loss
-renal failure
-lung damage
-splenic rupture
-sicle cell crises
-joint pain

Question 17

Eltrombopag

Answer 17

Oral Thrombopoietin agonist
-megakaryocytic growth factor
-increase platelets

Question 18

Romiplostim

Answer 18

Oral Thrombopoietin agonist
-megakaryocytic growth factor
-increase platelets