Hepatitis and HIV facts Flashcards
1
Q
HBV action
A
has key step of reverse transcriptase that can be blocked, uses GMP and AMP which makes those analogs more effective
2
Q
Interferon action
A
Block DNA and RNA
-inhibit transcription
-inhibit translation
-inhibit ER protein processing
-inhibit maturation
-inhibit virus release
3
Q
Ribavirin MOA
A
prevent vRNA pol in triphosphate form
-monophosphate inhibits IMP dehydrogenase preventing IMP to XMP and thus GTP synthesis
4
Q
A