Chemo facts Flashcards
1
Q
Proto oncogenes
A
usually control cell division, apoptosis and differentiation
when these are mutated and activated they cause cancer
2
Q
Tumour suppressor genes
A
usually suppress malignant cells, when these are mutated and inhibited they cause cancer
3
Q
alkylating agents
A
bind DNA and inhibit replication
4
Q
Alkylating agents side effects
A
Growth inhibition (no healing, hair growth, bone marrow, height, sperm production)
5
Q
Antimetabolite side effects
A
bone marrow toxicity
GI tract damage
6
Q
Topoisomerase inhibitor side effects
A
cardio toxicity
alopecia
7
Q
A
