Immunotherapy

Question 1

CTLA-4

Answer 1

receptor that down regulates T-Cells when binding to B7 proteins
cancer uses them to hide

Question 2

PD-1

Answer 2

receptor that down regulates T-Cells when bound to PD-L1 or 2 on tutor cells

Question 3

Nivolumab

Answer 3

PD-1/P-L1 inhibitor
prevents down regulation of immune cells from PD-1 binding
—–
-lung

Question 4

Pembrolizumab

Answer 4

PD-1/P-L1 inhibitor
prevents down regulation of immune cells from PD-1 binding
—–
-lung

Question 5

Atezolizumab

Answer 5

PD-1/P-L1 inhibitor
prevents down regulation of immune cells from PD-1 binding
—–
-lung

Question 6

Durvalumab

Answer 6

PD-1/P-L1 inhibitor
prevents down regulation of immune cells from PD-1 binding
—–
-several

Question 7

Ipilimumab

Answer 7

CTLA inhibitor
prevents down regulation of immune cells from CTLA binding
—–
-several

Question 8

Neoantigens

Answer 8

Vaccine for cancer developed for their pathogen
uses whole exome sequence to find proper antigens to provide and have immune system attack