Malaria facts

Question 1

uncomplicated malaria

Answer 1

fever, chills, muscle aches, fatigue

Question 2

complicated malaria

Answer 2

severe anemia, seizures, organ failure

Question 3

Sporozoite

Answer 3

The infective stage, get transfered from female mosquito

Question 4

Schizont

Answer 4

mature parasites that can release merozoite to infect further, develop in the RBC and to start in the hepatocytes

Question 5

Merozoite

Answer 5

The form of proliferation, produced by schizonts to infect more cells

Question 6

Trophozoite

Answer 6

Growth phase in the RBC to become a Schizont

Question 7

Hypnozoite

Answer 7

Dormant form in the liver

Question 8

Gametocyte

Answer 8

sexed merozoites that enter a new mosquito to proliferate and infect new individuals

Question 9

Malaria energy

Answer 9

From host hemoglobin AA via HB -> Heme then hemozoin

Question 10

Quinolones MOA

Answer 10

Build up in the food vacuoles to prevent heme polymerization into hemozoin causing increased pH and block of Hb proteolysis

Question 11

Folic acid antagonist side effect malaria

Answer 11

Promote gametocyte formation and therefore increase vector transmission