Pulmonary Function Tests Flashcards

1
Q

what pulmonary function test may be used in the initial diagnosis of asthma?

A

spirometry

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2
Q

what is a bronchial provacation test?

A

uses histamine, methacholine (a stable analogue of acetylcholine) or exposure to a nonpharmacologic agent like cold air to cause bronchoconstriction

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3
Q

what is methacholine?

A

is a cholinergic agonist that mimics the effects of the parasympathetic nervous system and causes bronchoconstriction

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4
Q

how is airway obstruction assessed?

A

following bronchial provacation using baseline and post beta-agonist measurements of FVC, FEV1, the ratio of FEV1 over FVC, and forced mid-expiratory flow 25 to 75%

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5
Q

when is reversible airway obstruction confirmed?

A

when post challenge data shows a 12% or greater improvement in FEV1 or FVC

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