Airway Limitation Mechanisms Flashcards

1
Q

what are the 4 most important mechanisms?

A
  1. loss of lung elastic recoil
  2. peribronchiolar fibrosis
  3. increased airway secretions
  4. airway smooth muscle
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2
Q

why does peribronchiolar fibrosis occur?

A

occurs due to an imbalance between the lungs repair and defense mechanisms

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3
Q

how is airway remodelling defined?

A

the persistent changes that occur within the structural components of the airways in response to inflammation

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4
Q

in COPD there is increased airway smooth muscle tone which causes what?

A

hyperactivity of the bronchi and bronchoconstriction related to persistent inflammation

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5
Q

what causes airway resistance?

A

airways become narrow

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