Pharm Other

Question 1

what other pharmacologic agents are used?

Answer 1

methylxanthines

Question 2

when are methylxanthines used?

Answer 2

as a third line treatment after inhaled anticholinergics or inhaled beta 2 agonists or when treating exacerbations

Question 3

what are mucolytics used for?

Answer 3

also a third line therapy and can be used especially in patients with significant mucus hyper-secretion

Question 4

what is Roflumilast?

Answer 4

a PDE 4 inhibitor
- works to promote smooth muscle relaxation by preventing the breakdown of cyclic AMP
- it is an oral therapy
- used if patient has high risk of acute exacerbation despite being on long acting inhaled therapy