Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Review / Wrong Answers > Psych drugs 1 > Flashcards

Psych drugs 1 Flashcards

1
Q

Tazamelteon

A

Melatonin receptor agonist Safe for insomnia in geriatric patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Flumazenil

A

MOA: Competitive antagonist at GABA benzo receptor Used for treatment of Benzo and non-benzo hypnotic overdose May precipitate seizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Trifluoperazine

A

“-azine” = star gazing

First generation antipsychotic (mostly D2 antagonist activity) - mostly treats positive schizo sx

High potency (more extra-pyramidal symptoms and less effect at other receptors)

Used for schizophrenia (+), acute psychotic episodes, acute agitation, Tourette’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Olanzapine

A

quiet please, ONLY whispering is appropriate

Second generation antipsychotic (D2 + 5HT-2 antagonist effects) - treats both (+) and (-) schizo sx

Used for schizophrenia, treatment resistant depression, OCD, Tourette’s

Side effects: H1 antagonist sedation, a1 antagonist orthostatic hypotension, muscarinic antagonism

metabolic symptoms (weight gain, dyslipidemia, hyperglycemia) - Olanzapine has highest risk

Less extra-pyramidal side effects than FGA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Clozapine

A

Closet

Second generation antipsychotic (D2 + 5HT-2 antagonist effects) - treats both (+) and (-) schizo sx

Used for schizophrenia, treatment resistant depression, OCD, Tourette’s

Side effects: H1 antagonist sedation, a1 antagonist orthostatic hypotension, muscarinic antagonism (Clozapine has highest risk), metabolic symptoms

Clozapine specific = agranulocytosis, myocarditis, reduced seizure threshold

Less extra-pyramidal side effects than FGA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Morphine

A

Opioid agonist (block pre-synaptic Ca2+ channels and opens post-synaptic K+ channels) Used for chronic pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Chlorpromazine

A

Sketchy = “color-pro” paint brand

First generation antipsychotic (mostly D2 antagonist activity) - mostly treats positive schizo sx

Low potency (less extra-pyramidal symptoms + anticholinergic, antihistamine, and a1-blocking effects)

Used for schizophrenia (+), acute psychotic episodes, acute agitation, Tourette’s

Side effect - corneal deposits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Fentanyl

A

Opioid agonist (block pre-synaptic Ca2+ channels and opens post-synaptic K+ channels) Used for chronic pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Midazolam

A

MOA: Short-acting Benzodiazepine (“All A.M.”) Facilitates action of GABA-A receptor by increasing frequency of Cl- channel opening

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Alprazolam

A

MOA: Short-acting Benzodiazepine (“All A.M.”) Facilitates action of GABA-A receptor by increasing frequency of Cl- channel opening

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Thioridazine

A

Sketchy = color THEORY wheel

First generation antipsychotic (mostly D2 antagonist activity) - mostly treats positive schizo sx

Low potency (less extra-pyramidal symptoms + anticholinergic, antihistamine, and a1-blocking effects)

Used for schizophrenia (+), acute psychotic episodes, acute agitation, Tourette’s

Side effects - retinal deposits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Eszoplicone

A

Non-benzo hypnotic Binds to GABA-A receptor (same site at Benzos) Used for sleep onset AND maintenance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Thiopental

A

Barbiturate - binds to allosteric site of GABA-A receptor to increase duration of Cl- channel opening Very fast acting and short lasting (due to redistribution to fat and skeletal muscle) Can be used for induction of anesthesia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Trihexyphenidyl

A

Anti-muscarinic

Balances out cholinergic effects to improve tremor and rigidity of Parkinsons with no effect on bradykinesia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Primidone

A

Barbiturate - binds to allosteric site of GABA-A receptor to increase duration of Cl- channel opening Used to essential tremor and seizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Ziprasidone

A

Zipper

Second generation antipsychotic (D2 + 5HT-2 antagonist effects) - treats both (+) and (-) schizo sx

Used for schizophrenia, treatment resistant depression, OCD, Tourette’s

Side effects: H1 antagonist sedation, a1 antagonist orthostatic hypotension, muscarinic antagonism, metabolic symptoms

Less extra-pyramidal side effects than FGA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Codeine

A

Anti-tussive opioid agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Quetiapine

A

QUIET please, only whispering is appropriate

Second generation antipsychotic (D2 + 5HT-2 antagonist effects) - treats both (+) and (-) schizo sx

Used for schizophrenia, treatment resistant depression, OCD, Tourette’s

Side effects: H1 antagonist sedation, a1 antagonist orthostatic hypotension, muscarinic antagonism, metabolic symptoms

Less extra-pyramidal side effects than FGA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Dantrolene

A

Muscle relaxant that prevents further release of Ca2+ from Ryanidine receptors Treats malignant hyperthermia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Methadone

A

Sketchy - DONE timer on withdrawal pool

Long-acting mu opioid agonist Used for opioid withdrawal symptoms/addiction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Bromocriptine

A

Dopamine agonist

Used for Parkinons and acromegaly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Zaleplon

A

Non-benzo hypnotic Binds to GABA-A receptor (same site at Benzos) Used for sleep onset (not maintenance - short half-life)

23
Q

Diazepam

A

MOA: Long-acting Benzodiazepine Facilitates action of GABA-A receptor by increasing frequency of Cl- channel opening

24
Q

Etomidate

A

Sketchy - The Intimidator

IV anesthetic - Potentiates GABA-A

Used for induction of anesthesia

Preserves cardiac stability

25
Halothane
Inhaled anesthetic (volatile) Unknown MOA More soluble - slow onset and longer duration Hepatotoxicity, malignant hyperthermia
26
Risperidone
quiet please, only WHISPERING is appropriate Second generation antipsychotic (D2 + 5HT-2 antagonist effects) - treats both (+) and (-) schizo sx Used for schizophrenia, treatment resistant depression, OCD, Tourette's Side effects: H1 antagonist sedation, a1 antagonist orthostatic hypotension, muscarinic antagonism, metabolic symptoms Less extra-pyramidal side effects than FGA - Risperidone has highest risk of EPS
27
Dextramethorphan
Sketchy - Orphan on cough drop bag Anti-tussive opioid agonist Also antagonist of NMDA receptor
28
Naltrexone
Opioid antagonist Used to reverse acute opioid toxicity Can precipitate withdrawals
29
Ariprazole
quiet please, only whispering is APPROPRIATE Second generation antipsychotic (D2 + 5HT-2 antagonist effects) - treats both (+) and (-) schizo sx Used for schizophrenia, treatment resistant depression, OCD, Tourette's Side effects: H1 antagonist sedation, a1 antagonist orthostatic hypotension, muscarinic antagonism, metabolic symptoms Less extra-pyramidal side effects than FGA
30
Chlordiazepoxide
MOA: Long-acting Benzodiazepine Facilitates action of GABA-A receptor by increasing frequency of Cl- channel opening
31
Buprenorphine
Sketchy - blueprint near pool exit Long-acting partial mu opioid agonist Used for withdrawal symptoms/addiction Can cause withdrawal in patients taking full opioid agonists
32
Haloperidol
First generation antipsychotic (mostly D2 antagonist activity) - mostly treats positive schizo sx High potency (more extra-pyramidal symptoms and less effect at other receptors) Used for schizophrenia (+), acute psychotic episodes, acute agitation, Tourette's
33
Pramipexole
Dopamine receptor agonist Used to treat Parkisons and restless leg syndrome
34
Tramadol
Weak opioid agonist Also inhibits 5-HT and NE reuptake Used for chronic pain
35
Fluphenazine
"-azine" = star gazing First generation antipsychotic (mostly D2 antagonist activity) - mostly treats positive schizo sx High potency (more extra-pyramidal symptoms and less effect at other receptors) Used for schizophrenia (+), acute psychotic episodes, acute agitation, Tourette's
36
Propofol
IV anesthetic - Potentiates GABA-A Used for induction and maintenance of anesthesia
37
Ropinirole
Dopamine agonist Used to treat Parkinons and restless leg syndrome May cause impulse control disorders
38
Levodopa
Dopamine precursor that can cross BBB Used to treat Parkisons
39
Enflurane
Inhaled anesthetic (volatile) Unknown MOA More soluble - slow onset and longer duration Nephrotoxicity, malignant hyperthermia
40
Ketamine
IV anesthetic - inhibits NMDA receptor Used for induction of anesthesia Causes dissociative anesthesia (eyes open) Can cause emergence reactions (hallucination, colorful dreams)
41
Loperamide
Anti-diarrheal opioid agonist
42
Diphenoxylate
Anti-diarrheal opioid agonist
43
Nitrous oxide
Inhaled anesthetic (gaseous) Unknown MOA Less soluble - faster onset and shorter duration
44
Carbidopa
Inhibitor of peripheral DOPA decarboxylase (prevents conversion of L-DOPA to DA in the periphery) Given with L-DOPA to treat Parkinsons Decreased peripheral side effects of L-DOPA (N/V, arrhythmias, hypotension) Increased CNS side effects of L-DOPA
45
Naloxone
Opioid antagonist Used to reverse acute opioid toxicity Can precipitate withdrawals
46
Selegiline
MOA-B inhibitor (so MOA cannot break down DA) Increases levels of DA in the CNS
47
Amantadine
Enhances effects of endogenous dopamine by increasing its synthesis/release and inhibiting its reuptake Can treat motor symptoms of Parkinsons
48
Zolpidem
Non-benzo hypnotic Binds to GABA-A receptor (same site at Benzos) Used for sleep onset (not maintenance - short half-life)
49
Ramelteon
Melatonin receptor agonist Safe for insomnia in geriatric patients
50
Triazolam
MOA: Short-acting Benzodiazepine ("All A.M.") Facilitates action of GABA-A receptor by increasing frequency of Cl- channel opening
51
Benztropine
Anti-muscarinic Balances out cholinergic effects to improve tremor and rigidity of Parkinsons with no effect on bradykinesia
52
Oxazepam
MOA: Short-acting Benzodiazepine Facilitates action of GABA-A receptor by increasing frequency of Cl- channel opening
53
Tolcapone
Inhibits COMT (COMT usually converts L-DOPA to inactive form), leading to increased availability of L-DOPA Works peripherally and centrally
54
Entacapone
Inhibits COMT (COMT usually converts L-DOPA to inactive form), leading to increased availability of L-DOPA Only works peripherally

Review / Wrong Answers (140 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions