proteomics Flashcards

1
Q

what is two-dimensional gel electrophoresis (2DE)?

A

a gel-based method which separates proteins based on isoelectric focusing point and molecular weight

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2
Q

what is multi-dimensional liquid chromatography (MDLC)?

A

a column based method which uses two different columns that separate proteins based on two different physical characteristics (e.g. molecular weight and charge)

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3
Q

what do microarrays look for?

A

Changes in the mRNA levels
Changes in the transcriptome

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4
Q

what is genomics?

A

the study of the total DNA content of a cell or tissue

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5
Q

what is proteomics?

A

the study of the total protein content of a cell or tissue

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6
Q

what is transcriptomics?

A

the study of the total mRNA content of a cell or tissue

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7
Q

what is metabolomics?

A

the study of the total metabolic content of a cell or tissue

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