glucose metabolism Flashcards
which enzyme is used in glycolysis and gluconeogenesis?
3-phosphoglycerate kinase.
During strenuous exercise, the NADH formed in the glyceraldehyde 3-phosphate dehydrogenase reaction in skeletal muscle must be reoxidised to NAD + if glycolysis is to continue. what is the most important reaction involved in the reoxidation of NADH?
pyruvate → lactate.
the anaerobic conversion of 1 mol of glucose to 2 mol of lactate by fermentation is accompanied by a net gain of what?
2 mol of ATP
what is the metabolic function of the pentose phosphate pathway?
to generate NADPH and pentoses for the biosynthesis of fatty acids and nucleic acids.
What are the primary metabolic fates of pyruvate?
acetyl CoA
ethanol
lactate
What is the function of liver glycogen degradation?
for glucose to export to other tissues when glucose levels are low
What is the name of the pathway that converts non-carbohydrate molecules into glucose?
gluconeogenesis
What two 3-carbon molecules are generated by the cleavage of fructose-1,6-bisphosphate?
glyceraldehyde-3-phosphate and dihydroxyacetone phosphate
What is the net organic products formed during the oxidation of one molecule of glucose to two molecules of pyruvate via glycolysis?
2 ATP + 2 NADH
Which enzymes found in glycolysis catalyses a ketose to aldose isomerisation?
Triose phosphate isomerase
What enzymes found in glycolysis catalyses an aldose to ketose isomerisation?
Phosphoglucose isomerase
What enzymes found in glycolysis produces ATP as a product?
Pyruvate kinase
What is not an intermediate in the glycolytic pathway by which glucose is oxidized to pyruvate?
Glucose 1-phosphate
what are the intermediates in the glycolytic pathway by which glucose is oxidized to pyruvate?
3-phosphoglycerate
Fructose 1,6-bisphosphate
Glyceraldehyde 3-phosphate
Phosphoenolpyruvate
What must be regenerated for glycolysis to proceed?
NAD+
